Application of Sigma Metrics for the Assessment of Quality Assurance in Clinical Biochemistry Laboratory in India: A Pilot Study     

Singh B  Goswami B  Gupta VK  Chawla R  Mallika V 《Indian journal of clinical biochemistry : IJCB》2011,26(2):131-135

Ensuring quality of laboratory services is the need of the hour in the field of health care. Keeping in mind the revolution ushered by six sigma concept in corporate world, health care sector may reap the benefits of the same. Six sigma provides a general methodology to describe performance on sigma scale. We aimed to gauge our laboratory performance by sigma metrics. Internal quality control (QC) data was analyzed retrospectively over a period of 6 months from July 2009 to December 2009. Laboratory mean, standard deviation and coefficient of variation were calculated for all the parameters. Sigma was calculated for both the levels of internal QC. Satisfactory sigma values (>6) were elicited for creatinine, triglycerides, SGOT, CPK-Total and Amylase. Blood urea performed poorly on the sigma scale with sigma <3. The findings of our exercise emphasize the need for detailed evaluation and adoption of ameliorative measures in order to effectuate six sigma standards for all the analytical processes.  相似文献   

Improving Reading Comprehension through Holistic Intervening and Tutoring During After-School with High Risk Minority Elementary School Students     

Kaprea F. Johnson  Abha Gupta  Hana Rosen  Howard Rosen 《Mentoring & Tutoring: Partnership in Learning》2013,21(4):431-443

The current study took a quasi-experimental approach investigating the effect of a holistic after-school intervention, on reading comprehension measured by the Gray Oral Reading Test (GORT)-4 on at-risk students in Grade 2 through Grade 5. Analysis of Variance was used to investigate the relationship between pre- and post-intervention scores. The study showed encouraging results. The 91 student participants showed gains in their GORT-4 total scores after the intervention. Results of after-school tutoring lend support to the use of peer-tutoring in afterschool in the elementary schools. Due to the exploratory nature of the study in a single school, there are constraints on generalizability and utility of findings to other schools across the board.  相似文献   

The role of materialism on social,emotional and behavioural difficulties for British adolescents     

Pam Maras  Amy Moon  Taveeshi Gupta  Nicole Gridley 《Emotional and Behavioural Difficulties》2013,18(4):362-380

The relationship between materialism and social-emotional behavioural difficulties (SEBDs) was assessed by comparing a sample of adolescents receiving in-school behavioural support with adolescents not receiving any support. All participants completed the Youth Materialism Scale and the Strengths and Difficulties Questionnaire. Binary logistic regression indicated that adolescents who reported higher levels of materialism were more likely to be classified into a group considered ‘at-risk’ for developing conduct and peer problems. Hierarchical logistic regression assessed the moderation of behavioural support and indicated that adolescents in receipt of behavioural support who reported higher levels of materialism were at a greater risk of hyperactivity in comparison to those who receive support but reported lower levels of materialism. For adolescents not receiving behavioural support, less materialistic attitudes placed them at a greater risk of hyperactivity. These findings highlight the importance of distinguishing between different SEBD typologies and the potential effects of materialism during adolescence.  相似文献   

Current status,enablers ＆ barriers of implementing cellular manufacturing system in Indian industries     

Amit R. Dixit  Manish Gupta 《上海大学学报(英文版)》2013,(4):346-356

The cellular manufacturing （CM） has been proved as a well-known manufacturing strategy that helps to improve manufacturing efficiency and productivity by utilizing the philosophy of group technology. Large num- ber of papers has been published in the area of design issues of CM system. Unfortunately, the issues related to acceptability of CM in Indian industries are typically not examined rigorously as technical issues. This paper pre- sents the results of a survey carded out to find the status, enabler and barrier of implementing CM system in Indian industries.  相似文献   

晚期折返过程含石墨流体包裹体及其意义：以印度两个不同地体为例     

M.K.Panigrahi S.Gupta 《中国科技期刊研究》2007,23(1):53-64

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Protein nanotechnology — A powerful futuristic diagnostic technique     

P. D. Gupta  Manasi Dave  A. R. Vasavada 《Indian journal of clinical biochemistry : IJCB》2005,20(2):48-53

Healthcare can be maintained well, when diagnosis is quick, accurate, cost-effective and painless. DNA and RNA based diagnosis may not reveal the right information for certain diseases. Identification and quantification of proteins and their folding mechanism are very important in diagnosis of diseases. Small quantities of proteins, which generally escape from detection and are responsible for the diseases, now can be quantified by protein nanotechniques which aids in the diagnosis. In this review, we have summarized the recent developments in nanotechnologies such as protein microarrays, biosensors etc. and their application in diagnosis of diseases at proteomics level have also been discussed.  相似文献   

Young children's causal inferences   总被引：1，自引：0，他引：1  

P Das Gupta  P E Bryant 《Child development》1989,60(5):1138-1146

We report 2 experiments that show a striking development between the ages of 3 and 4 years in children's ability to make causal inferences about sequences of events. The task in the first experiment was to work out what had caused the change to an object that started out as odd (noncanonical) in 1 way and ended up as odd in 2 ways--starting, for example, as a broken cup and ending as a wet and broken cup. When asked to choose the instrument that had caused the change, 3-year-olds often selected the instrument that could have caused the initial state (a hammer, in our example) and not the instrument that would produce the change. 4-year-olds hardly ever made this mistake. In the second experiment, the 3-year-olds were able to make the correct choice when the change was from a canonical to a noncanonical state (cup-wet cup) but had much more difficulty when the change was from noncanonical to canonical (wet cup-dry cup). The difference was much smaller in the older group. The first of these tasks can be solved simply on the basis of knowledge that a particular instrument can cause a particular effect without reference to the initial state. The second task requires attention to the differences between initial and final state. We conclude that the ability to make genuine causal inferences develops between the ages of 3 and 4 years.  相似文献   

Education: From telos to technique?     

Anoop  Gupta 《Educational Philosophy and Theory》2008,40(2):266-276

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Analysis of SEVA TB ES-31 antigen specific immunoglobulins IgM, IgA and IgG in sera of sputum and culture positive pulmonary tuberculosis     

Sonika Gupta  Niraj Shende  Swati Banerjee  Satish Kumar  M. V. R. Reddy  Bhaskar C. Harinath 《Indian journal of clinical biochemistry : IJCB》2002,17(1):5-8

Tuberculosis remains major health problem in India and developing countries Immunodiagnosis has important role in screening, diagnosis and management of tuberculosis. SEVA TB ES-31 antigen has shown potential in detecting tuberculous IgG antibody in earlier studies from our laboratory. In the present study we have analysedSEVA TB ES-31 antigen specific immunoglobulinsIgM, IgA and IgG in clinically and bacteriologically confirmed pulmonary tuberculosis cases to determine the usefulness of specific immunoglobulin class in the diagnosis of patients attending the hospital. Of the 30 cases of pulmonary tuberculosis 25 (83.3%) were positive for IgG, 19 (63.3%) for IgM and 16 (53.3%) for IgA. On combining IgG and IgM positivity, sensitivity was increased to 93.3%. While combining IgG and IgA positivity, sensitivity increased to 90%. However specificity was decreased to 66.6% and 70% for both of these combinations respectively. It could be envisaged from this study that IgG antibody detection against ES-31 antigen showed acceptable sensitivity (83.3%) and specificity (86.6%) compared to IgM or IgA alone or in combination. When immune responses were analysed according to degree of sputum positivity, IgG response was observed to be predominant in all grades, compared to IgM or IgA antibody. The addition of IgM or IgA as an adjunct test increases the sensitivity but at the cost of specificity. Hence the detection of IgG alone is more useful compared to IgM or IgA assay, in detecting tuberculosis disease cases coming to the hospital.  相似文献   

Serum and urinary zinc in zinc miners and zinc smelters     

P. P. Singh  K. H. Komleh  A. K. Pendse  Rajkiran  R. C. Gupta 《Indian journal of clinical biochemistry : IJCB》1992,7(1):57-59

Serum (200.6±64.8 mg/dl) and urinary zinc (1186.0±265.5 mg/l.) of zinc miners at Zawar were significantly higher as compared to zinc smelter workers (Serum 89.7±9.9. mg/dl; Urine 590.0±32.1 mg/l.). Debari and Udaipur residents (Serum 104.0±18.6 mg/dl; Urine 735.0±180.2 mg/l.). This was most likely attributable to higher dietary zinc intake by zinc miners due to higher zinc content of foodstuffs grown in Zawar areas as compared to Debari and Udaipur.  相似文献